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老年期抑郁障碍患者功能磁共振成像特征 及对治疗转归预测的进展
房圆仇琦李霞
()
fszhuche.com:
老年期抑郁障碍是常见的老年期精神障碍,功能磁共振成像脑网络连接分析可以帮助阐 明与老年期抑郁障碍相关的大脑区域和功能。多项研究表明,老年期抑郁障碍存在 3 个突出的脑功能 网络:执行控制网络、默认模式网络和突显网络。现综述老年期抑郁障碍患者上述 3 个突出的脑功能网 络成像特点及对抑郁治疗效果的预测进展,以期对目前已有研究进行总结,为今后研究方向提供参考。
基金项目:上海市卫生和计划生育委员会青年基金(20184Y0298);国家重点研发计划(2018YFC2002302)
Functional magnetic resonance imaging and prediction of treatment outcome of late-life depression
Fang Yuan,Qiu Qi,Li Xia
()
Abstract:
Late-life depression(LLD)is a common senile mental disorder. Functional magnetic resonance imaging (fMRI) brain network connection analysis can help to clarify the brain regions and functions related to LLD. A number of studies have shown that there are three prominent brain functional networks in LLD: executive control network, default mode network and salience/emotional processing network. This paper summarizes the above three prominent characteristics of brain functional network imaging in LLD and the progress in predicting the therapeutic effect of depression, in order to summarize the existing research and provide reference for the future research direction.

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